St. John's Wort

St. John’s Wort has gained a great deal of attention for its use in minor depression. Its popularity has stemmed from its extensive use by physicians in Europe as a first agent of choice in the treatment of mild to moderate depression. There are a variety of studies that are claimed to support the use of St. John’s Wort in treating depression. Also, sales of this herb in Europe, based on physician recommendation, outperform the popular pharmaceutical Prozac. With approximately 18 million Americans potentially experiencing some level of depression in a given year from a variety of causes, it is attracting attention as a safe and natural alternative to current prescription therapies available in the U.S.

Most frequently reported uses include: Antiviral and Depression. Other reported uses include: Bruises, Sprains, Genitourinary, HIV and Retroviruses, Myalgia, Nervous Symptoms Associated With Menopause And PMS, Neuralgia and to heal wounds.

Precautions

General
Although no real evidence has been presented to support it, there is theoretically a potential for an interaction with tyramine-containing foods, so these foods should be avoided.

Allergy
Allergic reactions have occurred in a small percentage of individuals who use St. John's Wort.

Health Conditions
Should not be taken by individuals expereincing suicidal depression, psychosis or severe depression.

Photosensitivity
Based on pharmacology, animal data and human data may cause photosensitivity.

Side Effects
Fatigue and GI distress may occur in about 0.5 percent of the individuals who take St. John’s Wort.